Immunology

Summary
This was a randomized open-label study conducted over several months to compare budesonide/formoterol with inhaled albuterol in the treatment of acute exacerbations of asthma that were mild to moderate in severity. The study was conducted in an emergency department. Parameters measured were oxygen saturation, peak expiratory flow rate, respiratory rate, and subjective improvement measures.
 
Thirty-two patients were enrolled, and 17 were randomized to receive nebulized albuterol and 15 to receive budesonide/formoterol. All patients improved and there was no statistically significant difference between the two treatments.  
 
Reference
Chew KS, et al. A randomized open-label trial on the use of budesonide/formoterol (Symbicort) as an alternative reliever medication for mild to moderate asthma attacks. International Journal of Emergency Medicine 2012; 5:16.